What is the molecular formula of haloperidol?

The molecular formula of haloperidol is C21H23ClFNO2.

What is the molecular weight of haloperidol?

The molecular weight of haloperidol is 375.9 g/mol.

What is the role of haloperidol as?

Haloperidol has a role as a serotonergic antagonist, a first generation antipsychotic, a dopaminergic antagonist, an antidyskinesia agent, and an antiemetic.

What receptors does haloperidol primarily antagonize in the brain?

Haloperidol primarily antagonizes the dopamine receptor, mainly D2.

What are some of the psychotic disorders for which haloperidol is indicated for treatment?

Haloperidol is indicated for the treatment of schizophrenia, acute psychosis, Tourette syndrome, and other severe behavioral states.

What is the benefit of using first-generation antipsychotics like haloperidol for managing "positive" symptoms of schizophrenia?

First-generation antipsychotics like haloperidol are highly effective for managing symptoms such as hallucinations, aggression, disorganized speech, and psychomotor agitation.

What are some of the movement disorders induced by dopamine blockade that can be caused by haloperidol?

Movement disorders induced by dopamine blockade that can be caused by haloperidol include drug-induced parkinsonism, akathisia, dystonia, and tardive dyskinesia.

How does haloperidol compare to lower-potency first-generation antipsychotics in terms of side effects?

Haloperidol typically demonstrates the least amount of side effects within its class, but has a stronger disposition for causing extrapyramidal symptoms.

How is haloperidol's metabolism affected by genetically determined polymorphic CYP2D6 activity?

In vivo pharmacogenetic studies suggest that the metabolism of haloperidol may be modulated by genetically determined polymorphic CYP2D6 activity.

What newer generation antipsychotics have largely replaced first-generation antipsychotics like haloperidol?

Second- and third-generation antipsychotics such as risperidone, olanzapine, quetiapine, aripiprazole, clozapine, and lurasidone have largely replaced first-generation antipsychotics like haloperidol.

Products

MDMO-PPV

Name: MDMO-PPV
SKU: ACM177716595
Rating: 5 (1 reviews)

Catalog Number

ACM177716595

CAS

177716-59-5

IUPAC Name

4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one

Synonyms

Poly[2-methoxy-5-(3',7'-dimethyloctyloxy)-1,4-phenylenevinylene]

Application

MDMO-PPV can also be used in the fabrication of bulk heterojunction solar cells(BHJ).

Molecular Weight

Mn ~120,000

Molecular Formula

C21H23ClFNO2

Product Information

Description

MDMO-PPV is a dialkoxy substituted poly(p-phenylenevinylene) (PPV) based conjugating polymer which has long side chains that form flexible films for organic electronics. It is a piezoresistant polymer with HOMO and LUMO orbital positions at 5.4 and 3.4 eV, respectively. MDMO-PPV forms an active layer that can be used in photoconductive and electroluminescent applications

Canonical SMILES

COc1ccc(OCCC(C)CCCC(C)C)cc1C=C

InChI

InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

InChI Key

LNEPOXFFQSENCJ-UHFFFAOYSA-N

Melting Point

216 ℃

Flash Point

Not applicable

Solubility

soluble in Toluene, Xylene, THF, Chloroform, Chlorobenzene, Cyclohexanone

Storage

room temp

Complexity

451

Exact Mass

375.140135g/mol

Hazard Statements

H319

Heavy Atom Count

MDL Number

MFCD03458070

Monoisotopic Mass

375.140135g/mol

Precautionary Statements

P305+P351+P338

Rotatable Bond Count

Signal Word

Warning

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